![]() You may develop difficulties with swallowing as your condition progresses. ![]() Your health care team may give you medicine to treat these symptoms. You also may experience other emotional changes, such as fear, anxiety or loss of motivation. Receiving treatment for depression can make it easier to handle the other challenges of Parkinson's disease. You may experience depression, sometimes in the very early stages. Such cognitive problems aren't usually helped by medicines.ĭepression and emotional changes. These usually occur in the later stages of Parkinson's disease. You may experience cognitive problems, such as dementia, and thinking difficulties. Parkinson's disease is often accompanied by these additional problems, which may be treatable: Ongoing exposure to herbicides and pesticides may slightly increase your risk of Parkinson's disease. Men are more likely to develop Parkinson's disease than are women. However, your risks are still small unless you have many relatives in your family with Parkinson's disease. Having a close relative with Parkinson's disease increases the chances that you'll develop the disease. Work, social situations and medicine side effects are also different from those of an older person with Parkinson's disease and require special considerations. If a young person does have Parkinson's disease, genetic counseling might be helpful in making family planning decisions. People usually develop the disease around age 60 or older. It ordinarily begins in middle or late life, and the risk increases with age. Young adults rarely experience Parkinson's disease. Risk factors for Parkinson's disease include: Researchers have found the clumped alpha-synuclein protein in the spinal fluid of people who later develop Parkinson's disease. This is currently an important focus among Parkinson's disease researchers. It's found in all Lewy bodies in a clumped form that cells can't break down. Although many substances are found within Lewy bodies, scientists believe that an important one is the natural and widespread protein called alpha-synuclein, also called a-synuclein. Alpha-synuclein found within Lewy bodies.These are called Lewy bodies, and researchers believe these Lewy bodies hold an important clue to the cause of Parkinson's disease. ![]() Clumps of specific substances within brain cells are microscopic markers of Parkinson's disease. Researchers also have noted that many changes occur in the brains of people with Parkinson's disease, although it's not clear why these changes occur. Exposure to certain toxins or environmental factors may increase the risk of later Parkinson's disease, but the risk is small. However, certain gene variations appear to increase the risk of Parkinson's disease but with a relatively small risk of Parkinson's disease for each of these genetic markers. But these are uncommon except in rare cases with many family members affected by Parkinson's disease. Researchers have identified specific genetic changes that can cause Parkinson's disease. The cause of Parkinson's disease is unknown, but several factors appear to play a role, including: When dopamine levels decrease, it causes irregular brain activity, leading to problems with movement and other symptoms of Parkinson's disease. Many of the symptoms of Parkinson's are due to a loss of neurons that produce a chemical messenger in your brain called dopamine. In Parkinson's disease, certain nerve cells called neurons in the brain gradually break down or die. See a health care professional if you have any of the symptoms associated with Parkinson's disease - not only to diagnose your condition but also to rule out other causes for your symptoms. It may become hard to write, and your writing may appear small. Your speech may be more of a monotone rather than have the usual speech patterns. You may speak softly or quickly, slur, or hesitate before talking. You may have a decreased ability to perform unconscious movements, including blinking, smiling or swinging your arms when you walk. Or you may fall or have balance problems as a result of Parkinson's disease. ![]() The stiff muscles can be painful and limit your range of motion. Muscle stiffness may occur in any part of your body. ![]() You may drag or shuffle your feet as you try to walk. It may be difficult to get out of a chair. Your steps may become shorter when you walk. Over time, Parkinson's disease may slow your movement, making simple tasks difficult and time-consuming. Slowed movement, known as bradykinesia.The shaking may decrease when you are performing tasks. You may rub your thumb and forefinger back and forth. Rhythmic shaking, called tremor, usually begins in a limb, often your hand or fingers. Symptoms often begin on one side of the body and usually remain worse on that side, even after symptoms begin to affect the limbs on both sides. Early symptoms may be mild and go unnoticed. Parkinson's disease symptoms can be different for everyone. ![]()
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